Author

S. Subudhi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. M. Lauer· 2 shared N. Alatrakchi· 2 shared N. Hacohen· 2 shared P. Lei· 2 shared R. K. Jain· 2 shared R. T. Chung· 2 shared A. A. I. Deik· 1 shared A. Ali· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

G. M. Lauer

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Author profile →

5 papers

Recent·Most cited

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

K. L. Abbott, A. Ali, B. I. Reinfeld, A. A. I. Deik, S. Subudhi, M. D. Landis, R. A. Hongo, K. L. Young, T. Kunchok, C. S. Nabel, K. D. Crowder, J. R. Kent, M. L. L. Madariaga, R. K. Jain, K. E. Beckermann, , M. G. Vander Heiden

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

bioRxiv · Dec 24, 2023Cancer Biology

Losartan rewires ovarian cancer tumor-immune microenvironment and suppresses IGF-1 to amplify chemo-immunotherapy sensitivity

Y. Sun, Z. Yin, L. Wu, C. Yue, Y. Zhang, S. Subudhi, P. Lei, A. Muzikansky, L. Zhang, B. R. Rueda, R. K. Jain, L. Xu

This study shows losartan improves chemo-immunotherapy effectiveness in ovarian cancer by altering the tumor microenvironment and reducing IGF-1 signaling in cancer cells.

bioRxiv · Aug 31, 2023 · PreprintCancer Biology

Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

Z. Amoozgar, J. Ren, N. Wang, T. P. Uccello, P. Andersson, G. Ferraro, S. Rajan, P. Lei, S. Subudhi, K. Kawaguchi, R. E. Tay, I. L. Gomes Dos Santos, P. Huang, H.-J. Kim, D. Fukumura, R. Jain

This study shows that blocking VEGF, Ang2, and PD1 reprograms GBM endothelial cells into quasi-antigen-presenting cells, enhancing anti-tumor responses and controlling edema.

bioRxiv · Sep 3, 2022 · PreprintCancer Biology

Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity

A. S. Genshaft, S. Subudhi, A. Keo, J. D. Sanchez Vasquez, N. Conceicao-Neto, D. Mahamed, L. L. Boeijen, N. Alatrakchi, C. Oetheimer, M. Vilme, R. Drake, I. Fleming, N. Tran, C. Tzouanas, J. Joseph-Chazan, , A. Gehring

The paper develops a workflow for collecting and analyzing liver immune cells via fine-needle aspirates and single-cell RNA sequencing to better understand tissue-specific immunity in chronic hepatitis B.

bioRxiv · Nov 30, 2021 · PreprintImmunology

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

P. Tonnerre, D. Wolski, S. Subudhi, J. Al-Jabban, R. C. Hoogeveen, M. Damasio, H. K. Drescher, L. M. Bartsch, D. C. Tully, D. R. Sen, D. J. Bean, J. Brown, A. Torres-Cornejo, M. Robidoux, D. Kvistad, , G. M. Lauer

The paper shows that exhausted CD8 T cells do not fully recover functional memory after antigen removal in chronic HCV infection.

bioRxiv · Apr 3, 2021Immunology