Author

J. K. Dick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

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Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Assay:proteomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

G. T. Hart· 3 shared J. A. Sangala· 3 shared J. S. Miller· 2 shared J. Wu· 2 shared S. E. Hamilton· 2 shared A. Johnson· 1 shared A. Khaimraj· 1 shared A. Khaitan· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

G. T. Hart

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3 papers

Recent·Most cited

Phenotype and function of IL-10 producing NK cells in individuals with malaria experience.

S. A. McNitt, J. K. Dick, M. Hernandez Castaneda, J. A. Sangala, M. Pierson, M. Macchietto, K. S. Burrack, P. D. Crompton, K. B. Seydel, S. E. Hamilton, G. T. Hart

The paper shows that malaria-experienced individuals have NK cells producing more IL-10, which may reduce inflammation and protect against malaria symptoms.

bioRxiv · May 11, 2024Immunology

Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

J. K. Dick, J. A. Sangala, V. D. Krishna, A. Khaimraj, L. Hamel, S. M. Erickson, D. Hicks, Y. Soigner, L. E. Covill, A. Johnson, M. J. Ehrhardt, K. Ernste, P. Brodin, R. A. Koup, A. Khaitan, , G. T. Hart

This study identifies dysregulated antibody-mediated cellular responses in MIS-C, linking NK cell dysfunction to immune pathology and suggesting potential therapeutic interventions.

bioRxiv · Apr 16, 2024Immunology

Ablation of SYK kinase from primary human Natural Killer cells via CRISPR/Cas9 enhances cytotoxicity and cytokine production

J. D. Dahlvang, J. K. Dick, J. A. Sangala, E. J. Pomeroy, K. M. Snyder, J. M. Moushon, C. E. Thefaine, J. Wu, S. E. Hamilton, M. Felices, J. S. Miller, B. Walcheck, B. R. Webber, B. S. Moriarity, G. T. Hart

This study ablates SYK kinase in primary human NK cells using CRISPR/Cas9, finding it enhances cytotoxicity and cytokine production compared to other gene ablations.

bioRxiv · May 29, 2022 · PreprintImmunology