Author

G. T. Hart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. R. Webber· 1 shared B. S. Moriarity· 1 shared B. Traore· 1 shared B. Walcheck· 1 shared C. E. Thefaine· 1 shared C. Wang· 1 shared D. L. Narum· 1 shared D. Su· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

B. R. Webber

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ablation of SYK kinase from primary human Natural Killer cells via CRISPR/Cas9 enhances cytotoxicity and cytokine production

J. D. Dahlvang, J. K. Dick, J. A. Sangala, E. J. Pomeroy, K. M. Snyder, J. M. Moushon, C. E. Thefaine, J. Wu, S. E. Hamilton, M. Felices, J. S. Miller, B. Walcheck, B. R. Webber, B. S. Moriarity, G. T. Hart

This study ablates SYK kinase in primary human NK cells using CRISPR/Cas9, finding it enhances cytotoxicity and cytokine production compared to other gene ablations.

bioRxiv · May 29, 2022 · PreprintImmunology

C17orf53 defines a novel pathway involved in inter-strand crosslink repair

C. Wang, Z. Chen, D. Su, M. Tang, L. Nie, H. Zhang, X. Feng, R. Wang, X. Shen, M. Srivastava, M. E. McLaughlin, G. T. Hart, L. Li, J. Chen

This study identifies C17orf53 as a novel gene involved in inter-strand crosslink repair, showing its role in DNA replication and repair factor loading.

bioRxiv · Sep 5, 2019Biochemistry

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody dependent cellular cytotoxicity

G. Arora, G. T. Hart, J. Manzella-Lapeira, J. Y. A. Doritchamou, D. L. Narum, M. Thomas, J. Brzostowski, S. Rajagopalan, O. K. Doumbo, B. Traore, L. Miller, S. K. Pierce, P. Duffy, P. D. Crompton, S. A. Desai, E. O. Long

The paper shows that antibodies from malaria-exposed individuals activate NK cells to lyse infected red blood cells and inhibit parasite growth via ADCC.

bioRxiv · Mar 29, 2018Immunology