Author

S. E. Hamilton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

G. T. Hart· 2 shared J. A. Sangala· 2 shared J. K. Dick· 2 shared K. S. Burrack· 2 shared A. E. Frosch· 1 shared B. R. Webber· 1 shared B. S. Moriarity· 1 shared B. Walcheck· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersImmunology

G. T. Hart

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Author profile →

3 papers

Recent·Most cited

Phenotype and function of IL-10 producing NK cells in individuals with malaria experience.

S. A. McNitt, J. K. Dick, M. Hernandez Castaneda, J. A. Sangala, M. Pierson, M. Macchietto, K. S. Burrack, P. D. Crompton, K. B. Seydel, S. E. Hamilton, G. T. Hart

The paper shows that malaria-experienced individuals have NK cells producing more IL-10, which may reduce inflammation and protect against malaria symptoms.

bioRxiv · May 11, 2024Immunology

IL-15 complex-induced IL-10 enhances Plasmodium-specific CD4+ Tfh differentiation and antibody production

M. Bravo, T. Dileepan, M. Dolan, J. Hildebrand, J. Wolford, S. E. Hamilton, A. E. Frosch, K. S. Burrack

This study shows that IL-15 complex treatment increases IL-10 in NK cells, which promotes Tfh differentiation and antibody production against Plasmodium, improving survival from reinfection.

bioRxiv · Oct 6, 2023 · PreprintImmunology

Ablation of SYK kinase from primary human Natural Killer cells via CRISPR/Cas9 enhances cytotoxicity and cytokine production

J. D. Dahlvang, J. K. Dick, J. A. Sangala, E. J. Pomeroy, K. M. Snyder, J. M. Moushon, C. E. Thefaine, J. Wu, S. E. Hamilton, M. Felices, J. S. Miller, B. Walcheck, B. R. Webber, B. S. Moriarity, G. T. Hart

This study ablates SYK kinase in primary human NK cells using CRISPR/Cas9, finding it enhances cytotoxicity and cytokine production compared to other gene ablations.

bioRxiv · May 29, 2022 · PreprintImmunology