A dual-mechanism antibiotic targets Gram-negative bacteria and avoids drug resistance
J. K. Martin, M. Z. Wilson, G. M. Moore, J. P. Sheehan, A. Mateus, S. H.-J. Li, B. P. Bratton, H. Kim, J. D. Rabinowitz, A. Typas, M. M. Savitski, Z. Gitai
This paper identifies a dual-mechanism antibiotic, SCH-79797, that kills Gram-negative and Gram-positive bacteria with low resistance and outperforms combination treatments.
Cell · Jun 1, 2020Peer-reviewedMicrobiology