Bacteria-to-human protein networks reveal origins of endogenous DNA damage
J. Xia, L.-Y. Chiu, R. B. Nehring, M. A. Bravo Nunez, Q. Mei, M. Perez, Y. Zhai, D. M. Fitzgerald, J. P. Pribis, Y. Wang, C. W. Hu, R. T. Powell, S. A. LaBonte, A. Jalali, M. L. Matadamas Guzman, , S. M. Rosenberg
The paper identifies DNA-damaging proteins in E. coli and their human homologs, showing they promote endogenous DNA damage and are overrepresented in cancer drivers.
bioRxiv · Jun 26, 2018Cancer Biology