Author

S. M. Rosenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. Herman· 3 shared J. P. Pribis· 3 shared P. J. Hastings· 3 shared Y. Zhai· 3 shared D. Bates· 2 shared D. M. Fitzgerald· 2 shared J. Xia· 2 shared L. Garcia-Villada· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

C. Herman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ppGpp and RNA-Polymerase Backtracking Guide Antibiotic-Induced Mutable Gambler Cells

Y. Zhai, P. J. Minnick, J. P. Pribis, L. Garcia-Villada, P. J. Hastings, C. Herman, S. M. Rosenberg

The paper identifies the stringent starvation response as a key driver of ciprofloxacin-induced mutagenesis through RNA polymerase and ppGpp-mediated DNA-damage signaling.

bioRxiv · Jul 6, 2022Microbiology

Gamblers: an Antibiotic-induced Evolvable Cell Subpopulation Differentiated by Reactive-oxygen-induced General Stress Response

J. P. Pribis, L. Garcia-Villada, Y. Zhai, O. Lewin-Epstein, A. Wang, J. Liu, J. Xia, Q. Mei, D. M. Fitzgerald, J. Bos, R. Austin, C. Herman, D. Bates, L. Hadany, P. J. Hastings, S. M. Rosenberg

The paper shows ciprofloxacin induces antibiotic-resistant mutations by creating a subpopulation of cells with activated sigma-S response, which allows error-prone repair and generates cross-resistant mutants.

bioRxiv · Dec 11, 2018Microbiology

Bacteria-to-human protein networks reveal origins of endogenous DNA damage

J. Xia, L.-Y. Chiu, R. B. Nehring, M. A. Bravo Nunez, Q. Mei, M. Perez, Y. Zhai, D. M. Fitzgerald, J. P. Pribis, Y. Wang, C. W. Hu, R. T. Powell, S. A. LaBonte, A. Jalali, M. L. Matadamas Guzman, , S. M. Rosenberg

The paper identifies DNA-damaging proteins in E. coli and their human homologs, showing they promote endogenous DNA damage and are overrepresented in cancer drivers.

bioRxiv · Jun 26, 2018Cancer Biology