Author

J. L. Griffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Hakkinen· 1 shared A. Murgia· 1 shared B. Sahu· 1 shared C. B. Messner· 1 shared C. Castro· 1 shared G. Piedrafita· 1 shared H. Irjala· 1 shared J. Routila· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Hakkinen

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2 papers

Recent·Most cited

Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

O. Kauko, M. Turunen, P. Pihlajamaa, A. Hakkinen, R. M. Queiroz, M. Paakkonen, S. Ventela, M. Gaetani, S. Lundstrom, A. Murgia, B. Sahu, J. Routila, H. Irjala, J. L. Griffin, K. S. Lilley, , J. Taipale

The paper identifies common downstream mechanisms driven by lineage-specific oncogenes that regulate cell proliferation in various cancers.

bioRxiv · Sep 27, 2022 · PreprintCancer Biology

Single amino acid-promoted reactions link a non-enzymatic chemical network to the early evolution of enzymatic pentose phosphate pathway

G. Piedrafita, S. J. Varma, C. Castro, C. B. Messner, L. Szyrwiel, J. L. Griffin, M. Ralser

This paper shows how single amino acids can enhance non-enzymatic reactions similar to the pentose phosphate pathway, suggesting a stepwise evolution from environmental chemical networks to enzymatic metabolism.

bioRxiv · Aug 11, 2020Biochemistry