A. Hakkinen

Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

The paper identifies common downstream mechanisms driven by lineage-specific oncogenes that regulate cell proliferation in various cancers.

In vivo single-cell analysis using calcofluor - white staining detects high expression phenotype in L. lactis cultures engineered for hyaluronic acid production.

This paper uses calcofluor white staining and in vivo fluorescence confocal microscopy to detect high-expression phenotypes in L. lactis engineered for hyaluronic acid production, revealing significant heterogeneity in HA expression.

Transcription closed and open complex formation coordinate expression of genes with a shared promoter region

The paper models gene-pair transcription dynamics in E. coli, showing that co-expression requires compatible rate-limiting steps, validated by single-cell RNA measurements.