Author

J. L. Ostrop

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Diez-Sanchez· 1 shared C. L. Drurey· 1 shared H. T. Lindholm· 1 shared M. J. Oudhoff· 1 shared N. Parmar· 1 shared R. Maizels· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

A. Diez-Sanchez

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1 paper

Recent·Most cited

Developmental pathways regulate cytokine-driven effector and feedback responses in the intestinal epithelium

H. T. Lindholm, N. Parmar, C. L. Drurey, J. L. Ostrop, A. Diez-Sanchez, R. Maizels, M. J. Oudhoff

The paper investigates how cytokines regulate intestinal epithelial responses through developmental pathways, showing IL-13 induces goblet cells via NOTCH signaling and uses BMP signaling as a feedback loop in tuft cell hyperplasia.

bioRxiv · Jun 19, 2020Immunology