Author

J. L. Pulice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Kadoch· 1 shared C. S. Mitsiades· 1 shared D. C. Mitchell· 1 shared E. M. Garcia-Rivera· 1 shared G. M. Matthews· 1 shared J. A. Roth· 1 shared J. M. Chick· 1 shared J. M. Knapp· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. Kadoch

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Highly specific intracellular ubiquitination of a small molecule

W. Li, E. M. Garcia-Rivera, D. C. Mitchell, J. M. Chick, M. Maetani, J. M. Knapp, G. M. Matthews, R. Shirasaki, R. de Matos Simoes, V. Viswanathan, J. L. Pulice, M. G. Rees, J. A. Roth, S. P. Gygi, C. S. Mitsiades, , J. M. L. Ostrem

The paper identifies a small molecule, BRD1732, that is ubiquitinated in cells, leading to proteasome inhibition through accumulation of ubiquitin chains.

bioRxiv · Jan 26, 2024Biochemistry

Dosage amplification dictates oncogenic regulation by the NKX2-1 lineage factor in lung adenocarcinoma

J. L. Pulice, M. Meyerson

The paper identifies NKX2-1 dosage amplification as a critical driver in lung adenocarcinoma, showing it regulates enhancer accessibility, lineage addiction, and EGFR inhibitor resistance.

bioRxiv · Oct 26, 2023Cancer Biology