Author

J. Lapierre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. S. Hub· 2 shared C. R. Ojha· 1 shared F. Kashanchi· 1 shared J. Aman· 1 shared M. K. Muthu Karuppan· 1 shared M. Nair· 1 shared M. Rodriguez· 1 shared M. Toborek· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

J. S. Hub

Author profile →

3 papers

Recent·Most cited

Converging PMF calculations of antibiotic permeation across an outer membrane porin with sub-kilocalorie per mole accuracy

J. Lapierre, J. S. Hub

This paper investigates the convergence of potentials of mean force for antibiotic permeation through an outer membrane porin using advanced umbrella sampling techniques.

bioRxiv · Mar 27, 2023Biophysics

DNA opening during transcription initiation by RNA polymerase II in atomic detail

J. Lapierre, J. S. Hub

This study uses molecular dynamics simulations to reveal the atomic details of DNA opening during transcription initiation by RNA polymerase II, showing how protein loops interact with DNA to break hydrogen bonds and stabilize the open bubble.

bioRxiv · Feb 5, 2022Biophysics

ZIKA VIRUS INFECTION DURING PREGNANCY AND INDUCED BRAIN PATHOLOGY IN BECLIN1-DEFICIENT MOUSE MODEL

M. K. Muthu Karuppan, C. R. Ojha, M. Rodriguez, J. Lapierre, J. Aman, F. Kashanchi, M. Toborek, M. Nair, N. El-Hage

This study investigates the role of Beclin1 in ZIKV infection during pregnancy, showing growth impairments and brain pathology in offspring of Beclin1-deficient mice.

bioRxiv · Nov 15, 2019 · PreprintImmunology