Author

J. M. Guss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

J. L. Walshe· 2 shared J. P. Mackay· 2 shared A. P. G. Silva· 1 shared B. Atto· 1 shared D. A. Gell· 1 shared D. H. Tran· 1 shared H. Suga· 1 shared J. K. K. Low· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

J. L. Walshe

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2 papers

Recent·Most cited

Cyclic peptides can engage a single binding pocket through multiple, entirely divergent modes

K. Patel, L. J. Walport, J. L. Walshe, P. Solomon, J. K. K. Low, D. H. Tran, K. S. Mouradian, A. P. G. Silva, L. Wilkinson-White, J. M. Matthews, J. M. Guss, R. J. Payne, T. Passioura, H. Suga, J. P. Mackay

The paper identifies high-affinity, specific cyclic peptide inhibitors of BET bromodomains using RaPID screening, revealing diverse binding modes and structures.

bioRxiv · Nov 21, 2019Biochemistry

A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae

R. D. Latham, M. Torrado, B. Atto, J. L. Walshe, R. Wilson, J. M. Guss, J. P. Mackay, S. Tristram, D. A. Gell

This study identifies hemophilin, a heme-binding protein from Haemophilus haemolyticus, which inhibits non-typeable Haemophilus influenzae by heme starvation.

bioRxiv · May 15, 2019Biochemistry