D. D. Thomson

Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia

Heightened efficacy of anidulafungin when used in combination with manogepix or 5-flucytosine against Candida auris in vitro

This study shows that combining anidulafungin with manogepix or 5-flucytosine enhances antifungal efficacy against Candida auris in vitro.

Distinct cohorts of Aspergillus fumigatus transcription factors are required for epithelial damage occurring via contact- or soluble effector-mediated mechanisms

This study identifies distinct transcription factor cohorts required for early and late phases of epithelial damage caused by Aspergillus fumigatus.

Epithelial uptake of Aspergillus fumigatus drives efficient fungal clearance in vivo and is aberrant in Chronic Obstructive Pulmonary Disease (COPD)

The paper shows that airway epithelial cells efficiently kill inhaled Aspergillus fumigatus spores in vivo, but this process is impaired in COPD.

Aspergillus fumigatus drives tissue damage via iterative assaults upon mucosal integrity and immune homeostasis

This paper investigates how Aspergillus fumigatus causes lung damage by analyzing host responses to different fungal morphotypes and secreted products in cultured cells and a mouse model.

Courtship ritual of male and female nuclei during fertilisation in Neurospora crassa

This study tracks male and female nuclei during fertilization in Neurospora crassa using live-cell imaging, revealing novel dynamics of nuclear movement and polyspermy avoidance.