Author

J. M. Jacques

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Biophysics· 1

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Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Haagsma· 1 shared F. L. Nobrega· 1 shared L. Reese· 1 shared M. Dogterom· 1 shared S. J. J. Brouns· 1 shared T. Idema· 1 shared W. K. Spoelstra· 1 shared

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2019-2019 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. C. Haagsma

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1 paper

Recent·Most cited

CRISPR-based DNA and RNA detection with liquid-liquid phase separation

W. K. Spoelstra, J. M. Jacques, F. L. Nobrega, A. C. Haagsma, M. Dogterom, T. Idema, S. J. J. Brouns, L. Reese

This paper introduces a label-free CRISPR-based method for nucleic acid detection using liquid-liquid phase separation, showing that target sequence cleavage reduces turbidity.

bioRxiv · May 15, 2019Biophysics