Author

A. C. Haagsma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. L. Nobrega· 2 shared A. C. Fluit· 1 shared A. Muralidharan· 1 shared A. R. Costa· 1 shared B. A. van der Steen· 1 shared B. Estrada Bonilla· 1 shared D. F. van den Berg· 1 shared H. van den Bossche· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

F. L. Nobrega

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Accumulation of defense systems in phage resistant strains of Pseudomonas aeruginosa

A. R. Costa, D. F. van den Berg, J. Q. Esser, A. Muralidharan, H. van den Bossche, B. Estrada Bonilla, B. A. van der Steen, A. C. Haagsma, A. C. Fluit, F. L. Nobrega, P.-J. Haas, S. J. Brouns

The paper shows that Pseudomonas aeruginosa strains with more phage defense systems are more resistant to phages, and these systems often target different phage genera.

bioRxiv · Aug 12, 2022 · PreprintMicrobiology

CRISPR-based DNA and RNA detection with liquid-liquid phase separation

W. K. Spoelstra, J. M. Jacques, F. L. Nobrega, A. C. Haagsma, M. Dogterom, T. Idema, S. J. J. Brouns, L. Reese

This paper introduces a label-free CRISPR-based method for nucleic acid detection using liquid-liquid phase separation, showing that target sequence cleavage reduces turbidity.

bioRxiv · May 15, 2019Biophysics