Author

W. K. Spoelstra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Reese· 2 shared M. Dogterom· 2 shared A. C. Haagsma· 1 shared E. O. van der Sluis· 1 shared F. L. Nobrega· 1 shared J. M. Jacques· 1 shared S. J. J. Brouns· 1 shared T. Idema· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

L. Reese

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Non-spherical coacervate shapes in an enzyme driven active system

W. K. Spoelstra, E. O. van der Sluis, M. Dogterom, L. Reese

This study investigates how enzymatic activity influences the shape and stability of RNA coacervates, finding that PNPase affects morphology and degradation.

bioRxiv · Jan 27, 2020Biophysics

CRISPR-based DNA and RNA detection with liquid-liquid phase separation

W. K. Spoelstra, J. M. Jacques, F. L. Nobrega, A. C. Haagsma, M. Dogterom, T. Idema, S. J. J. Brouns, L. Reese

This paper introduces a label-free CRISPR-based method for nucleic acid detection using liquid-liquid phase separation, showing that target sequence cleavage reduces turbidity.

bioRxiv · May 15, 2019Biophysics