Author

J. M. Kanczler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:mouse· 3 Organism:human· 2 Organism:chicken / avian· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. I. Dawson· 4 shared R. O. C. Oreffo· 4 shared C. Echalier· 3 shared J. P. Wojciechowski· 3 shared K. M. Marshall· 3 shared M. M. Stevens· 3 shared T. Yang· 3 shared V. Jayawarna· 3 shared

Activity by Year

2023-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioengineering

J. I. Dawson

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Author profile →

5 papers

Recent·Most cited

Bioactive coatings on 3D printed polycaprolactone scaffolds for bone regeneration: a novel murine femur defect model for examination of the biomaterial capacity for repair.

K. M. Marshall, J. P. Wojciechowski, V. Jayawarna, A. Hasan, C. Echalier, S. J. P. Callens, T. Yang, J. M. Kanczler, J. I. Dawson, A. Mata, M. Salmeron-Sanchez, M. M. Stevens, R. O. C. Oreffo

This study evaluates bioactive coatings on 3D printed PCL-TMA900 scaffolds for bone regeneration using a murine femur defect model, finding that Laponite/BMP-2 coating significantly promotes bone formation without heterotopic bone formation.

bioRxiv · Dec 15, 2023Bioengineering

Bioactive coatings on 3D printed scaffolds for bone regeneration: Use of Laponite™ to deliver BMP-2 for bone tissue engineering - progression through in vitro, chorioallantoic membrane assay and murine subcutaneous model validation.

K. M. Marshall, J. P. Wojciechowski, C. Echalier, S. J. P. Callens, T. Yang, O. Ovrebo, V. Jayawarna, J. M. Kanczler, M. M. Stevens, J. I. Dawson, R. O. C. Oreffo

This paper evaluates Laponite-coated scaffolds for delivering BMP-2 to enhance bone regeneration, showing effective osteoinduction in vitro and in vivo with delayed use.

bioRxiv · Oct 25, 2023Bioengineering

Bioactive coatings on 3D printed scaffolds for bone regeneration: Translation from in vitro to in vivo models and the impact of material properties and growth factor concentration.

K. M. Marshall, J. P. Wojciechowski, V. Jayawarna, A. Hasan, C. Echalier, O. Ovrebo, T. Yang, J. M. Kanczler, A. Mata, M. Salmeron-Sanchez, M. M. Stevens, R. O. C. Oreffo

This study evaluates bioactive coatings on 3D-printed PCL-TMA scaffolds for bone regeneration, showing in vitro osteogenic response but no significant in vivo bone formation.

bioRxiv · Oct 22, 2023Bioengineering

Human bone tissue-derived ECM hydrogels: Controlling physicochemical, biochemical, and biological properties through processing parameters

Y.-H. Kim, G. Cidonio, J. M. Kanczler, R. O. Oreffo, J. I. Dawson

This study shows that adjusting bone powder size and digestion time can improve the properties of human bone ECM hydrogels for bone tissue engineering.

bioRxiv · Aug 3, 2023Bioengineering

Biofabrication of nanocomposite-based scaffolds containing human bone extracellular matrix for the differentiation of skeletal stem and progenitor cells

Y.-H. Kim, J. M. Kanczler, S. Lanham, A. Rawlings, M. Roldo, G. Tozzi, J. I. Dawson, G. Cidonio, R. O. C. Oreffo

This paper develops a nanocomposite bioink using human bone extracellular matrix, nanoclay, and alginate for 3D bioprinting to support osteogenic differentiation of bone marrow stromal cells in vitro and ex vivo.

bioRxiv · Apr 7, 2023 · PreprintBioengineering