Author

S. R. Ellis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:metabolomics· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. L. Marshall· 2 shared M. Claesen· 2 shared M. J. Q. Mantas· 2 shared N. Verbeeck· 2 shared R. M. A. Heeren· 2 shared R. S. E. Young· 2 shared S. J. Blanksby· 2 shared A. D. Postle· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

D. L. Marshall

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A High-Throughput Data-Independent Acquisition Workflow for Deep Characterisation of the sn-Isomer Lipidome

J. A. Michael, R. S. E. Young, R. Balez, L. J. Jekimovs, D. L. Marshall, B. L. J. Poad, T. W. Mitchell, S. J. Blanksby, C. S. Ejsing, S. R. Ellis

The paper introduces a high-throughput workflow for characterizing sn-isomer lipidomes, identifying more sn-isomer pairs and revealing differences between cell lines.

bioRxiv · Nov 4, 2023 · PreprintCell Biology

Integration of Multiple Spatial-Omics Modalities Reveals Unique Insights into Molecular Heterogeneity of Prostate Cancer

W. Zhang, X. Spotbeen, S. Vanuytven, S. Kint, T. Sarretto, F. Socciarelli, K. Vandereyken, J. Dehairs, J. Idkowiak, D. Wouters, J. I. Alvira Larizgoitia, G. Partel, A. Ly, V. de Laat, M. J. Q. Mantas, , J. V. Swinnen

This paper integrates multiple spatial-omics modalities in prostate cancer samples to reveal molecular heterogeneity and correlations between lipids and gene expression.

bioRxiv · Aug 28, 2023 · PreprintCancer Biology

Omics Scale Quantitative Mass Spectrometry Imaging of Lipids in Brain Tissue using a Multi-Class Internal Standard Mixture

M. Vandenbosch, S. M. Mutuku, M. J. Q. Mantas, N. H. Patterson, T. Hallmark, M. Claesen, R. M. A. Heeren, N. G. Hatcher, N. Verbeeck, K. Ekroos, S. R. Ellis

This paper introduces a method for quantitative mass spectrometry imaging of lipids in brain tissue using a multi-class internal standard mixture, revealing absolute lipid concentrations across multiple lipid classes.

bioRxiv · Jun 21, 2023Biochemistry

Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

S. R. Ellis, E. Halll, M. Panchal, B. Flinders, J. Madsen, G. Koster, R. M. A. Heeren, H. W. Clark, A. D. Postle

The paper uses mass spectrometry imaging with isotopic tracers to visualize phosphatidylcholine metabolism in mouse lungs, revealing metabolic processes and acyl chain remodeling.

bioRxiv · Oct 7, 2020Biochemistry

Metabolic plasticity in cancer activates apocryphal pathways for lipid desaturation

R. S. E. Young, A. P. Bowman, E. D. Williams, K. D. Tousignant, C. L. Bidgood, V. R. Narreddula, R. Gupta, D. L. Marshall, B. L. Poad, C. C. Nelson, S. R. Ellis, R. M. Heeren, M. Sadowski, S. J. Blanksby

The paper reveals metabolic plasticity in cancer through isomer-resolved lipidomics, identifying apocryphal pathways for lipid desaturation and their impact on lipid structure and function.

bioRxiv · Jun 7, 2020 · PreprintBiochemistry