Author

J. Mantell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Microbiology· 1

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Assay:electronic health records· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

M. P. Dodding· 3 shared P. Verkade· 3 shared U. Borucu· 3 shared D. M. Paul· 2 shared D. N. Woolfson· 2 shared J. A. Cross· 2 shared J. F. Weijman· 2 shared K. J. Surridge· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

M. P. Dodding

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Author profile →

5 papers

Recent·Most cited

CryoET reveals actin filaments within platelet microtubules

C. Tsuji, M. Bradshaw, M. Allen, M. L. Jackson, J. Mantell, U. Borucu, A. W. Poole, P. Verkade, I. Hers, D. M. Paul, M. Dodding

The paper uses cryoET to show cofilin-bound F-actin within platelet microtubules, revealing physiological actin-microtubule hybrids formed under mechanical stress.

bioRxiv · Nov 24, 2023Cell Biology

Molecular architecture of the autoinhibited kinesin-1 lambda particle

J. F. Weijman, S. Y. Kadapalakere, K. J. Surridge, J. A. Cross, U. Borucu, J. Mantell, D. N. Woolfson, C. Schaffitzel, M. P. Dodding

The paper integrates computational structure prediction with electron microscopy to reveal the coiled-coil architecture of the autoinhibited compact form of kinesin-1.

bioRxiv · Apr 28, 2022Cell Biology

Molecular mechanism for kinesin-1 direct membrane recognition

Z. Anton, J. F. Weijman, C. Williams, E. R. R. Moody, J. Mantell, Y. Y. Yip, J. A. Cross, T. A. Williams, R. A. Steiner, M. Crump, D. N. Woolfson, M. P. Dodding

This paper identifies a conserved amphipathic helix in kinesin-1 light chains that mediates direct membrane binding, challenging the previous understanding of lysosome positioning.

bioRxiv · Jan 20, 2021Cell Biology

Bacterial flagella disrupt host cell membranes and interact with cytoskeletal components

E. B. Wolfson, J. Elvidge, A. Tahoun, T. Gillespie, J. Mantell, S. P. McAteer, Y. Rossez, E. Paxton, F. Lane, D. J. Shaw, A. C. Gill, J. Steveni, P. Verkade, A. Blocker, A. Mahajan, D. L. Gally

This study investigates how bacterial flagella from E. coli and Salmonella species interact with host cell membranes and cytoskeletal components, showing membrane disruption and actin polymerization effects.

bioRxiv · Feb 12, 2020 · PreprintMicrobiology

In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen

D. M. Paul, J. Mantell, U. Borucu, J. Coombs, K. J. Surridge, J. M. Squire, P. Verkade, M. P. Dodding

The paper uses cryo-electron tomography to show F-actin within microtubule lumens in induced cellular projections, revealing new cytoskeletal configurations.

bioRxiv · Nov 18, 2019Cell Biology