Author

J. Martynowicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

W. J. Sullivan· 3 shared L. Augusto· 2 shared P. H. Amin· 2 shared R. C. Wek· 2 shared J. S. Doggett· 1 shared K. R. Carlson· 1 shared M. Kaplan· 1 shared N. S. Alakhras· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

W. J. Sullivan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TgIF2K-B is an eIF2α kinase in Toxoplasma gondii that responds to oxidative stress and optimizes pathogenicity

L. Augusto, J. Martynowicz, P. H. Amin, K. R. Carlson, R. C. Wek, W. J. Sullivan

This study identifies TgIF2K-B as an eIF2α kinase in Toxoplasma gondii that mitigates oxidative stress and supports pathogenicity by enabling cyst formation and resisting macrophage activation.

bioRxiv · Sep 24, 2020Microbiology

Efficacy of Guanabenz Combination Therapy Against Chronic Toxoplasmosis Across Multiple Mouse Strains

J. Martynowicz, J. S. Doggett, W. J. Sullivan

This study evaluates combination therapies for chronic toxoplasmosis in mice, finding strain-dependent efficacy and antagonistic effects in some drug pairs.

Antimicrobial Agents and Chemotherapy · Aug 20, 2020Peer-reviewedMicrobiology

Toxoplasma gondii co-opts the unfolded protein response to enhance migration and dissemination of infected host cells

L. Augusto, J. Martynowicz, P. H. Amin, N. S. Alakhras, M. Kaplan, R. C. Wek, W. J. Sullivan

This study shows Toxoplasma gondii triggers the unfolded protein response in host cells to enhance migration and dissemination of infected cells through IRE1-mediated actin remodeling.

bioRxiv · Apr 14, 2020Microbiology