Author

J. Mehtonen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

M. Heinaniemi· 3 shared O. Lohi· 3 shared A. Malyukova· 2 shared M. Lahnalampi· 2 shared O. Sangfelt· 2 shared P. Polonen· 2 shared S. Teppo· 2 shared A. Hagstrom-Andersson· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

M. Heinaniemi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia

A. Malyukova, M. Lahnalampi, T. Falques-Costa, P. Polonen, M. Sipola, J. Mehtonen, S. Teppo, J. Viiliainen, O. Lohi, A. Hagstrom-Andersson, M. Heinaniemi, O. Sangfelt

bioRxiv · Mar 27, 2023 · PreprintCancer Biology

Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1 positive pediatric leukemia identifies drug-targetable transcription factor activities

J. Mehtonen, S. Teppo, M. Lahnalampi, A. Kokko, R. Kaukonen, L. Oksa, M. Bouvy-Liivrand, A. Malyukova, S. Laukkanen, P. I. Makinen, S. Rounioja, P. Ruusuvuori, O. Sangfelt, R. Lund, T. Lonnberg, , M. Heinaniemi

This study uses scRNA-seq to analyze B-lymphoid differentiation and leukemic cell states in ETV6-RUNX1-positive pediatric leukemia, identifying drug-targetable transcription factor activities.

Genome Medicine · Nov 20, 2020Peer-reviewedCancer Biology

Immunogenomic landscape of hematological malignancies

O. Dufva, P. Polonen, O. Bruck, M. Keranen, J. Mehtonen, A. Kumar, C. Heckman, S. Siitonen, K. Granberg, S.-K. Leivonen, L. Meriranta, S. Leppa, M. Nykter, O. Lohi, M. Heinaniemi, S. Mustjoki

This study links immunological features to cancer subtypes, genetic alterations, and patient survival in hematological malignancies using integrated genomic and transcriptomic data.

bioRxiv · Apr 26, 2019Immunology