Author

S. Leppa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Ristimäki· 1 shared C. Haglund· 1 shared C. Heckman· 1 shared E. Elbasani· 1 shared H. Monzo· 1 shared H. Seppänen· 1 shared J. Carlson· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Kumar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in an ovarian carcinoma model

H. Monzo, M. Hyytiäinen, E. Elbasani, K. Kalander, J. Wall, L. Moyano-Galceran, J. Tanjore Ramanathan, J. Jukonen, P. Laakkonen, A. Ristimäki, J. Carlson, K. Lehti, S. Salehi, P. Puolakkainen, C. Haglund, , P. M. Ojala

This study evaluates anti-SSEA-4 CAR-T cells in ovarian cancer models, showing efficacy against SSEA-4 positive cells but highlighting dose-dependent toxicity.

bioRxiv · Sep 2, 2022Cancer Biology

Immunogenomic landscape of hematological malignancies

O. Dufva, P. Polonen, O. Bruck, M. Keranen, J. Mehtonen, A. Kumar, C. Heckman, S. Siitonen, K. Granberg, S.-K. Leivonen, L. Meriranta, S. Leppa, M. Nykter, O. Lohi, M. Heinaniemi, S. Mustjoki

This study links immunological features to cancer subtypes, genetic alterations, and patient survival in hematological malignancies using integrated genomic and transcriptomic data.

bioRxiv · Apr 26, 2019Immunology