Author

O. Bruck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Mustjoki· 3 shared P. Polonen· 2 shared A. Jerez· 1 shared A. Kreutzman· 1 shared A. Kumar· 1 shared A. M. Hurtado· 1 shared C. Heckman· 1 shared C. Munoz-Calleja· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

S. Mustjoki

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Author profile →

3 papers

Recent·Most cited

Integrative Analysis of Histological Textures and Lymphocyte Infiltration in Renal Cell Carcinoma using Deep Learning

O. Brummer, P. Polonen, S. Mustjoki, O. Bruck

This study uses deep learning to analyze histological textures and lymphocyte infiltration in renal cell carcinoma, finding associations between tissue features and clinical outcomes.

bioRxiv · Aug 15, 2022 · PreprintCancer Biology

Somatic Mutations in Clonally Expanded T-lymphocytes in Patients with Chronic Graft-Versus-Host Disease

G. Park, S. Mustjoki, D. Kim, J. Huuhtanen, S. Lundgren, R. K. Khajuria, A. M. Hurtado, C. Munoz-Calleja, L. Cardenoso, V. Gomez-Garcia de Soria, T. H. Chen-Liang, S. Eldfors, P. Ellonen, S. Hannula, O. Bruck, , M. A. I. Keranen

This study identifies somatic mutations in clonally expanded T-cells in chronic GvHD patients, showing they drive persistent activation and resistance to mTOR inhibitors.

bioRxiv · Aug 31, 2019 · PreprintImmunology

Immunogenomic landscape of hematological malignancies

O. Dufva, P. Polonen, O. Bruck, M. Keranen, J. Mehtonen, A. Kumar, C. Heckman, S. Siitonen, K. Granberg, S.-K. Leivonen, L. Meriranta, S. Leppa, M. Nykter, O. Lohi, M. Heinaniemi, S. Mustjoki

This study links immunological features to cancer subtypes, genetic alterations, and patient survival in hematological malignancies using integrated genomic and transcriptomic data.

bioRxiv · Apr 26, 2019Immunology