Author

J. N. Alumasa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:structural biology· 1

Frequent Co-Authors

C. M. Dunham· 2 shared K. C. Keiler· 2 shared A. B. Kuzmishin Nagy· 1 shared A. E. Jerse· 1 shared A. Mehrani· 1 shared D. Hosangadi· 1 shared E. D. Hoffer· 1 shared H. A. Nguyen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

C. M. Dunham

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 9, 2023

Antibiotic that inhibits trans-translation blocks binding of EF-Tu to tmRNA but not to tRNA

N. Marathe, H. A. Nguyen, J. N. Alumasa…·K. C. Keiler

This paper identifies KKL-55, a tetrazole-based antibiotic that specifically inhibits EF-Tu binding to tmRNA without affecting tRNA binding, suggesting a new target for antibiotic development.

DOI 10.1101/2023.06.09.544387

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologybioRxivPreprintJun 4, 2020

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Z. D. Aron, A. Mehrani, E. D. Hoffer…·K. C. Keiler

The paper describes the development of ribosome rescue inhibitors that clear drug-resistant Neisseria gonorrhoeae in vivo through a novel mechanism involving ribosomal conformational changes.

DOI 10.1101/2020.06.04.132530

mousestructural biology

𝕏 PostBluesky