Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis
M. Inoue, M. Enomoto, Y. Koike, M. A. Di Grappa, X. Zhao, K. Yip, S. H. Huang, J. N. Waldron, M. Ikura, F.-F. Liu, S. V. Bratman
This study shows that albumin oxidation causes redox imbalance, leading to inflammation-independent NETosis and lung-specific cancer metastasis.
bioRxiv · Feb 28, 2018Cancer Biology