Author

S. H. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Research Focus:cancer & tumor microenvironment· 3 Assay:imaging· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

G. Shvets· 3 shared A. Ward· 2 shared R. Truong· 2 shared A. Bosque· 1 shared A. Danesh· 1 shared A. Gramatica· 1 shared A. Macedo· 1 shared A. Mahalanabish· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

G. Shvets

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Inverted transflection spectroscopy of live cells using metallic grating on elevated nanopillars

A. Mahalanabish, S. H. Huang, G. Shvets

This paper introduces Inverted Transflection Spectroscopy (ITS) for live cell analysis, demonstrating its ability to measure protein concentrations and characterize cell adhesion kinetics.

bioRxiv · Sep 19, 2023Biophysics

Proliferative Exhausted CD8 T Cells Exacerbate Long-lasting Anti-tumor Effects in Human Papillomavirus Positive Head and Neck Squamous Cell Carcinoma

D. Cheng, K. Qiu, Y. Rao, M. Mao, L. Li, Y. Wang, Y. Song, J. Chen, X. Yi, X. Shao, S. H. Huang, Y. Zhang, X. Chen, S. Wu, S. Yu, , J. Ren

The paper identifies a proliferative exhausted CD8+ T cell cluster in HPV-positive HNSCC that correlates with better patient survival and suggests potential therapeutic implications.

bioRxiv · Oct 27, 2022Immunology

Probing the Drug Dynamics and Mode-of-Action of Chemotherapeutics Using Metasurface-Enhanced Infrared Reflection Spectroscopy of Live Cells

P.-T. Shen, S. H. Huang, Z. Huang, J. J. Wilson, G. Shvets

This study uses MEIRS to monitor real-time drug dynamics and mode-of-action of TRIP in live cancer cells, showing changes in cellular signals and correlation with phenotypic responses.

bioRxiv · Apr 8, 2022 · PreprintBiophysics

Monitoring the effects of chemical stimuli on live cells with metasurface-enhanced infrared reflection spectroscopy

S. H. Huang, J. Li, Z. Fan, R. Delgado, G. Shvets

This study uses MEIRS to monitor live cell responses to chemical stimuli in real-time, detecting morphological, adhesive, lipid, and signaling changes.

bioRxiv · Jun 30, 2021Bioengineering

Selective BCL-XLAntagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs

Y. Ren, s. h. huang, A. Macedo, A. Ward, W. Conce, T. Klevorn, L. Leyre, D. Chan, R. Truong, T. Rohwetter, P. Zumbo, F. Dundar, D. Betel, C. Kovacs, E. Benko, , B. Jones

This study shows BCL-XL antagonists reduce HIV in a cell model of latency but not in ex vivo reservoirs, suggesting resistance in true reservoir cells.

bioRxiv · Nov 25, 2020 · PreprintMicrobiology

HIV-specific T-cell responses reflect substantive in vivo interactions with infected cells despite long-term therapy

E. Stevenson, A. Ward, R. Truong, A. Thomas, S. H. Huang, T. Dilling, S. Terry, J. Bui, T. Mota, A. Danesh, G. Lee, A. Gramatica, P. Khadka, W. C. Alberto, R. Gandhi, , R. B. Jones

The paper shows HIV-specific T-cell responses persist despite long-term ART, indicating ongoing recognition of infected cells and suggesting the reservoir is not fully immunologically silent.

bioRxiv · Aug 28, 2020Immunology

Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis

M. Inoue, M. Enomoto, Y. Koike, M. A. Di Grappa, X. Zhao, K. Yip, S. H. Huang, J. N. Waldron, M. Ikura, F.-F. Liu, S. V. Bratman

This study shows that albumin oxidation causes redox imbalance, leading to inflammation-independent NETosis and lung-specific cancer metastasis.

bioRxiv · Feb 28, 2018Cancer Biology