J. Nakano

An ALS-associated mutant KIF5A forms oligomers and aggregates and induces neuronal toxicity

This study shows that an ALS-associated KIF5A mutant forms oligomers and aggregates, leading to neuronal toxicity rather than loss of function.

Structural model of microtubule dynamics inhibition by Kinesin-4 from the crystal structure of KLP-12 - tubulin complex

The paper reports the crystal structure of KLP-12-tubulin complex, revealing how KLP-12 inhibits microtubule dynamics by altering tubulin curvature.