Author

J. Nangalia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:clustering· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

I. Martincorena· 2 shared L. Moore· 2 shared N. Williams· 2 shared P. J. Campbell· 2 shared A. Damaskou· 1 shared A. L. Godfrey· 1 shared A. Menzies· 1 shared A. R. Green· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

I. Martincorena

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Author profile →

3 papers

Recent·Most cited

The longitudinal dynamics and natural history of clonal haematopoiesis

M. A. Fabre, J. G. de Almeida, E. Fiorillo, E. Mitchell, A. Damaskou, J. Rak, V. Orru, M. Marongiu, M. Vijayabaskar, J. Baxter, C. Hardy, F. Abascal, M. S. Chapman, N. Williams, J. Nangalia, , G. S. Vassiliou

This study tracks clonal haematopoiesis clones over time, finding that mutation type influences growth rates and malignant risk.

bioRxiv · Aug 12, 2021Cancer Biology

Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution

N. Williams, J. Lee, L. Moore, E. J. Baxter, J. Hewinson, K. J. Dawson, A. Menzies, A. L. Godfrey, A. R. Green, P. J. Campbell, J. Nangalia

This study reconstructs the phylogeny of myeloproliferative neoplasms using whole-genome sequencing, revealing early mutation acquisition and lifelong clonal evolution leading to cancer.

bioRxiv · Nov 9, 2020 · PreprintCancer Biology

The mutational landscape of normal human endometrial epithelium

L. Moore, D. Leongamornlert, T. H. Coorens, M. A. Sanders, P. Ellis, K. Dawson, F. Maura, J. Nangalia, P. S. Tarpey, S. F. Brunner, H. Lee-Six, R. Rahbari, S. Moody, Y. Hooks, K. Mahbubani, , M. R. Stratton

This study characterizes the mutational landscape of normal human endometrial epithelium, revealing age-related mutation burdens and driver mutations in cancer genes.

bioRxiv · Dec 24, 2018Cancer Biology