Author

J. Nomburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Cancer Biology· 1

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Approach:statistical model· 5 Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

J. A. DeCaprio· 4 shared M. Meyerson· 3 shared G. J. Starrett· 2 shared J. A. Doudna· 2 shared A. Giobbie-Hurder· 1 shared A. Goldstein· 1 shared A. Lahiri· 1 shared A. Mwanga· 1 shared

Activity by Year

2019-2024 · peak 2/yr

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10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

J. A. DeCaprio

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Author profile →

6 papers

Recent·Most cited

Birth of new protein folds and functions in the virome

J. Nomburg, N. Price, J. A. Doudna

The paper identifies new viral protein folds and functions by analyzing a database of predicted viral protein structures, revealing conserved immune evasion mechanisms across different viral species.

bioRxiv · Jan 22, 2024 · PreprintMicrobiology

Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi

B. A. Adler, M. J. Al-Shimary, J. R. Patel, E. Ambruster, D. Colognori, E. J. Charles, K. V. Miller, A. Lahiri, M. Trinidad, R. Boger, J. Nomburg, S. Beurnier, M. L. Cui, R. Barrangou, V. K. Mutalik, , B. F. Cress

The paper develops a CRISPRi-ART system to knock down protein expression in diverse bacteriophages and identifies essential genes, including many with unknown functions.

bioRxiv · Sep 18, 2023 · PreprintMicrobiology

The Transcriptome Architecture of Polyomaviruses

J. Nomburg, W. Zou, T. C. Frost, C. Datta, S. Vasudevan, G. J. Starrett, M. J. Imperiale, M. Meyerson, J. A. DeCaprio

The paper characterizes the transcriptome architecture of polyomaviruses using RNA sequencing data, revealing pervasive wraparound transcription and novel conserved transcripts.

bioRxiv · Nov 12, 2021 · PreprintMicrobiology

An international report on bacterial communities in esophageal squamous cell carcinoma

J. Nomburg, S. Bullman, D. Nasrollahzadeh, E. A. Collisson, B. Abedi-Ardekani, L. O. Akoko, J. R. Atkins, G. C. Buckle, S. Gopal, N. Hu, B. Kaimila, M. Khoshnia, R. Malekzadeh, D. Menya, B. T. Mmbaga, , K. Van Loon

This study identifies bacterial communities associated with esophageal squamous cell carcinoma (ESCC) tumors and finds similar enrichment of oral bacteria in both saliva and tumor microbiomes of ESCC patients.

bioRxiv · Sep 29, 2021Microbiology

Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

J. Nomburg, M. Meyerson, J. A. DeCaprio

This study identifies canonical and non-canonical subgenomic RNAs in SARS-CoV-2, showing their consistent generation across isolates and infection conditions.

bioRxiv · Apr 28, 2020Microbiology

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

G. J. Starrett, M. Thakuria, T. Chen, C. Marcelus, J. Cheng, J. Nomburg, A. R. Thorner, M. K. Slevin, W. Powers, R. T. Burns, C. Perry, A. Piris, F. C. Kuo, G. Rabinowits, A. Giobbie-Hurder, , J. A. DeCaprio

This study characterizes virus-positive and virus-negative Merkel cell carcinomas using deep sequencing, identifying molecular differences and clinical associations with immunosuppression and survival.

bioRxiv · Mar 24, 2019Cancer Biology