Author

J. R. Patel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lahiri· 1 shared A. R. Healy· 1 shared B. A. Adler· 1 shared B. F. Cress· 1 shared D. Colognori· 1 shared D. F. Savage· 1 shared E. Ambruster· 1 shared E. E. Shine· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. Lahiri

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi

B. A. Adler, M. J. Al-Shimary, J. R. Patel, E. Ambruster, D. Colognori, E. J. Charles, K. V. Miller, A. Lahiri, M. Trinidad, R. Boger, J. Nomburg, S. Beurnier, M. L. Cui, R. Barrangou, V. K. Mutalik, , B. F. Cress

The paper develops a CRISPRi-ART system to knock down protein expression in diverse bacteriophages and identifies essential genes, including many with unknown functions.

bioRxiv · Sep 18, 2023 · PreprintMicrobiology

Model colibactins exhibit human cell genotoxicity in the absence of host bacteria

E. E. Shine, M. Xue, J. R. Patel, A. R. Healy, Y. V. Surovtseva, S. Herzon, J. M. Crawford

This study shows that free model colibactins induce DNA double-strand breaks in human cells without requiring host bacteria, revealing mechanisms of genotoxicity and product diversification in colibactin biosynthesis.

bioRxiv · Sep 29, 2018Cancer Biology