N. Price

Birth of new protein folds and functions in the virome

The paper identifies new viral protein folds and functions by analyzing a database of predicted viral protein structures, revealing conserved immune evasion mechanisms across different viral species.

Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses

This study identifies broad-spectrum antiviral agents effective against multiple RNA virus families, including arboviruses and respiratory pathogens.

A wipe-based stool collection and preservation kit for microbiome community profiling

This paper introduces and validates a DESS wipe-based method for stool collection and preservation, showing high accuracy and diversity maintenance compared to freezing and commercial kits.

Linking genomic signatures of selection to expression variation and direct evidence of local adaptation

The paper links genomic signatures of selection to expression variation and finds that GxE genes show higher differentiation and selective constraint, suggesting their role in cold adaptation.

In the presence of population structure: From genomics to candidate genes underlying local adaptation

The paper compares mixed linear models and Spearman correlations for identifying SNPs associated with climate, finding that SNPs from both methods are enriched for local adaptation but only GEMMA-associated SNPs show functional constraint and fitness QTL linkage.

Drought adaptation in nature by extensive genetic loss-of-function

The paper identifies gene knockouts linked to drought adaptation in Arabidopsis thaliana using whole genome sequences and satellite data, showing their adaptive value.