Author

J. O. Strubbe

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

E. V. Pavlov· 1 shared J. F. Conway· 1 shared J. N. Bazil· 1 shared J. R. Schrad· 1 shared K. N. Parent· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

E. V. Pavlov

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1 paper

Recent·Most cited

The Mitochondrial Permeability Transition Phenomenon Elucidated by Cryo-EM Reveals the Genuine Impact of Calcium Overload on Mitochondrial Structure and Function

J. O. Strubbe, J. R. Schrad, E. V. Pavlov, J. F. Conway, K. N. Parent, J. N. Bazil

The study uses cryo-EM to show how calcium overload causes mitochondrial permeability transition by forming calcium phosphate granules and inner membrane fragmentation, and reveals cyclosporin A's role in preserving inner membrane structure.

Scientific Reports · Jan 13, 2021Peer-reviewedCell Biology