Author

J. P. Connelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

S. M. Pruett-Miller· 3 shared A. Budhraja· 1 shared B. Johannesson· 1 shared C. Florian· 1 shared C. Mullighan· 1 shared D. Bhattacharya· 1 shared F. J. Monsma· 1 shared H. A. Pizzato· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

S. M. Pruett-Miller

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers

H. A. Pizzato, P. Alonso-Guallart, J. Woods, B. Johannesson, J. P. Connelly, T. A. Fehniger, J. Atkinson, S. M. Pruett-Miller, F. J. Monsma, D. Bhattacharya

This study genetically modifies human pluripotent stem cells to evade immune rejection in mice by knocking out HLA genes and adding inhibitory factors, leading to persistent teratomas in immunocompetent models.

bioRxiv · Jun 27, 2023Immunology

Short Tandem Repeat Profiling via Next Generation Sequencing for Cell Line Authentication

Y.-H. Chen, J. P. Connelly, C. Florian, X. Cui, S. M. Pruett-Miller

This study compares NGS-based STR profiling with traditional STR-CE for cell line authentication, finding NGS offers better sequence context, sensitivity, and multiplexing.

bioRxiv · Feb 25, 2023Cell Biology

Heme-Sensing Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

K. H. Smith, A. Budhraja, J. Lynch, K. Roberts, J. C. Panetta, J. P. Connelly, M. E. Turnis, S. M. Pruett-Miller, J. D. Schuetz, C. Mullighan, J. T. Opferman

The paper identifies the heme-sensing pathway as a regulator of MCL-1 expression in B-lineage acute leukemia, showing that modulating this pathway enhances sensitivity to BH3-mimetics.

bioRxiv · Apr 10, 2020Cancer Biology