Author

M. E. Turnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

J. T. Opferman· 2 shared A. Budhraja· 1 shared C. Mullighan· 1 shared J. C. Panetta· 1 shared J. D. Schuetz· 1 shared J. Lynch· 1 shared J. P. Connelly· 1 shared K. H. Smith· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

J. T. Opferman

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2 papers

Recent·Most cited

Inducible genetic ablation of Immt induces a lethal disruption of the MICOS complex

S. M. Rockfield, M. E. Turnis, R. Rodriguez-Enriquez, M. Bathina, S. K. Ng, S. Pelletier, P. Vogel, J. T. Opferman

This study shows that deleting Immt, which encodes MIC60, in mice causes lethal disruption of the MICOS complex, leading to intestinal defects and bone marrow issues.

bioRxiv · Aug 22, 2023 · PreprintPhysiology

Heme-Sensing Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

K. H. Smith, A. Budhraja, J. Lynch, K. Roberts, J. C. Panetta, J. P. Connelly, M. E. Turnis, S. M. Pruett-Miller, J. D. Schuetz, C. Mullighan, J. T. Opferman

The paper identifies the heme-sensing pathway as a regulator of MCL-1 expression in B-lineage acute leukemia, showing that modulating this pathway enhances sensitivity to BH3-mimetics.

bioRxiv · Apr 10, 2020Cancer Biology