Author

J. P. Stoye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

G. R. Young· 3 shared M. W. Yap· 2 shared A. Guedan· 1 shared I. A. Taylor· 1 shared K. N. Bishop· 1 shared M. A. Cottee· 1 shared R. Hall· 1 shared R. Harvey· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersEvolutionary Biology

G. R. Young

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Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

R. Hall, A. Guedan, M. W. Yap, G. R. Young, R. Harvey, J. P. Stoye, K. N. Bishop

This paper shows that SARS-CoV-2 ORF6 inhibits mRNA export by interacting with Rae1, suppressing antiviral responses and aiding viral replication.

bioRxiv · Feb 8, 2022Microbiology

Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli mice allows protection from multiple retroviruses

M. W. Yap, G. R. Young, R. Varnaite, S. Morand, J. P. Stoye

The paper identifies a duplicated Fv1 gene in Mus caroli mice that provides resistance to multiple retroviruses, suggesting evolutionary pressure from diverse viral threats.

bioRxiv · Oct 11, 2019Evolutionary Biology

Structure of D. melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

M. A. Cottee, S. C. Letham, G. R. Young, J. P. Stoye, I. A. Taylor

The paper presents the crystal structure of dARC1 and compares it to mammalian ARC and retroviral CA proteins, showing structural divergence and functional adaptation.

bioRxiv · Jul 10, 2019Evolutionary Biology