Author

J. Parolek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Organism:mouse· 1

Frequent Co-Authors

C. G. Burd· 2 shared A. Hilderink· 1 shared A. S. Klymchenko· 1 shared B. Sarkar· 1 shared D. I. Danylchuk· 1 shared J. C. M. Holthuis· 1 shared J. Piehler· 1 shared K. Maeda· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

C. G. Burd

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bridge-like lipid transfer protein family member 2 suppresses ciliogenesis

J. Parolek, C. G. Burd

This study identifies BLTP2 as a negative regulator of ciliogenesis, functioning as a lipid transfer protein between ER and tubular endosomes.

bioRxiv · Dec 7, 2023Cell Biology

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

T. Sokoya, J. Parolek, M. M. Foged, D. I. Danylchuk, M. Bozan, B. Sarkar, A. Hilderink, M. Philippi, L. D. Botto, P. A. Terhal, O. Maekitie, J. Piehler, Y. Kim, C. G. Burd, A. S. Klymchenko, , J. C. M. Holthuis

The paper shows pathogenic SMS2 variants disrupt lipid landscapes in the secretory pathway by trapping sphingomyelin in the ER and altering cholesterol and glycerophospholipid distributions.

bioRxiv · Apr 2, 2022Cell Biology

J. Parolek · henhao