Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease
Y. Huang, J. Wang, D. Chin, V. Mancino, J. Pham, H. Li, K. Jiang, A. Ram, C. Poon, P.-Y. Ho, J. Peti-Peterdi, G. Gyarmati, K. R. Hallows, E. J. Chung
This study develops an oral nanoparticle delivery system for metformin in ADPKD, showing improved kidney targeting and bioavailability compared to conventional methods.
bioRxiv · Oct 18, 2022 · PreprintBioengineering