Author

D. Chin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. Poon· 2 shared E. J. Chung· 2 shared J. Wang· 2 shared A. Pathak· 1 shared A. Plotkin· 1 shared A. Ram· 1 shared A. Shah· 1 shared A. W. Ensminger· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

C. Poon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner

A. Pathak, S. Palasalava, M. V. Knott, B. Colon, E. Ciervo, Y. Zhou, J. Mitchell, O. T. Pumar, H. K. A. Wong, L. Zhang, N. Susic, K. H. Shah, K. Kay, D. Chin, S. Johnson, , D. Bayik

This study shows GABA receptor B signaling promotes GBM growth in females through immune mechanisms, with sex-specific effects on survival and treatment outcomes.

bioRxiv · Jul 18, 2024Cancer Biology

Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease

Y. Huang, J. Wang, D. Chin, V. Mancino, J. Pham, H. Li, K. Jiang, A. Ram, C. Poon, P.-Y. Ho, J. Peti-Peterdi, G. Gyarmati, K. R. Hallows, E. J. Chung

This study develops an oral nanoparticle delivery system for metformin in ADPKD, showing improved kidney targeting and bioavailability compared to conventional methods.

bioRxiv · Oct 18, 2022 · PreprintBioengineering

Nanoparticle-mediated microRNA-145 Delivery for Vascular Smooth Muscle Cell Phenotype Modulation and Atherosclerosis Treatment

D. Chin, C. Poon, J. Wang, J. Joo, V. Ong, Z. Jiang, K. Cheng, A. Plotkin, G. A. Magee, E. J. Chung

This study develops miR-145-loaded nanoparticles to target VSMC phenotype switching and atherosclerosis, showing reduced plaque growth and restored contractile markers in vitro and in mice.

bioRxiv · Sep 9, 2020 · PreprintBioengineering

Priming In A Permissive Type I-C CRISPR-Cas System Reveals Distinct Dynamics Of Spacer Acquisition And Loss

C. Rao, D. Chin, A. W. Ensminger

This study examines primed adaptation in a type I-C CRISPR-Cas system of Legionella pneumophila, revealing dynamics of spacer acquisition, loss, and sequence constraints.

bioRxiv · May 12, 2017Microbiology