Author

J. R. Sims

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. F. R. Ascencao· 1 shared D. Dibitetto· 1 shared K. Feng· 1 shared M. B. Smolka· 1 shared R. Freire· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

C. F. R. Ascencao

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1 paper

Recent·Most cited

ATR Inhibitors as Potent Modulators of DNA End Resection Capacity

D. Dibitetto, J. R. Sims, C. F. R. Ascencao, K. Feng, R. Freire, M. B. Smolka

This study shows that long-term ATR inhibition reduces DNA end resection and DNA repair efficiency in cancer cells, offering a strategy to enhance PARP inhibitor sensitivity.

bioRxiv · Jan 13, 2020 · PreprintCancer Biology