Cancer BiologybioRxiv
The MNK1/2-eIF4E axis contributes to phenotype switching, melanoma progression, and resistance to immunotherapy.
F. Huang, C. Goncalves, M. Bartish…·S. del Rincon
This study identifies the MNK1/2-eIF4E axis as a driver of melanoma phenotype switching, progression, and immunotherapy resistance, with potential therapeutic targeting.