Author

J. Sakanari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. A. Bulman· 3 shared J. F. Urban· 2 shared M. Mitreva· 2 shared A. Leontovyc· 1 shared A. M. Irish· 1 shared B. A. Rosa· 1 shared B. Beerntsen· 1 shared C. Barinka· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPharmacology & Toxicology

C. A. Bulman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Y. Lin, H. Jung, C. A. Bulman, J. Ng, R. Vinck, C. O'Beirne, M. S. Moser, N. Tricoche, R. Peguero, R. W. Li, J. F. Urban, P. Le Pape, F. Pagniez, M. Moretto, T. Weil, , G. Gasser

Simple derivatives of the well-known antifungal drug fluconazole were found to be highly effective in vivo against fungal infections and potent against parasitic nematodes causing lymphatic filariasis and soil-transmitted helminths.

bioRxiv · Jun 28, 2023Pharmacology & Toxicology

Uncovering the essential roles of human GCP 2 orthologs in Caenorhabditis elegans.

L. Panska, S. Nedvedova, V. Vacek, D. Krivska, L. Konecny, F. Knop, Z. Kutil, L. Skultetyova, A. Leontovyc, L. Ulrychova, J. Sakanari, M. Asahina, C. Barinka, M. Macurkova, J. Dvorak

This study investigates the roles of human GCP2 orthologs in C. elegans by knocking out three orthologous genes and analyzing their effects on physiology and tissue localization.

bioRxiv · Feb 27, 2023 · PreprintBiochemistry

De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells

D. P. Jasmer, B. A. Rosa, R. Tyagi, C. A. Bulman, B. Beerntsen, J. F. Urban, J. Sakanari, M. Mitreva

The paper identifies 10 inhibitors that cause irreparable damage to intestinal cells of parasitic nematodes, showing potential for broad-spectrum anthelmintics.

bioRxiv · Nov 22, 2019Pathology

Chagas disease serological test performance in United States blood donor specimens

J. D. Whitman, C. A. Bulman, E. L. Gunderson, A. M. Irish, R. L. Townsend, S. Stramer, J. Sakanari, C. Bern

This study evaluates the performance of four FDA-cleared serological tests for Chagas disease in US blood donors, finding varying sensitivity and specificity across tests and birth regions.

bioRxiv · Aug 9, 2019Microbiology