SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients
J. A. Perez-Bermejo, S. S. Kang, S. J. Rockwood, C. R. Simoneau, D. A. Joy, G. N. Ramadoss, A. C. Silva, W. R. Flanigan, H. Li, K. Nakamura, J. D. Whitman, M. Ott, B. R. Conklin, T. C. McDevitt
This study infects human iPSC-derived cardiac cells with SARS-CoV-2 and identifies novel cytopathic features in COVID-19 patient hearts, including myofibrillar fragmentation and DNA loss in cardiomyocytes.
bioRxiv · Aug 25, 2020Cell Biology