J. Salje

The intracellular bacterium Orientia tsutsugamushi hijacks the adaptor protein BICD2 for dynein-based motility

This study identifies how Orientia tsutsugamushi uses ScaC to recruit BICD2 for dynein-based motility, revealing a mechanism for bacterial transport within host cells.

Orientia tsutsugamushi: analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacterium.

This study analyzes the mobilome of Orientia tsutsugamushi, revealing intact RAGEs and prophage remnants, indicating ongoing lateral gene transfer in this obligate intracellular bacterium.

The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state

This paper identifies and characterizes two distinct developmental forms of Orientia tsutsugamushi, intracellular and extracellular bacteria, showing differences in morphology, protein expression, and entry mechanisms into host cells.

Dual RNA-seq provides insight into the biology of the neglected intracellular human pathogen Orientia tsutsugamushi

The paper uses dual RNA-seq to study the transcriptional architecture and host-pathogen interactions of Orientia tsutsugamushi, identifying antisense regulation and strain-specific immune responses.

Clickable methionine as a universal probe for labelling intracellular bacteria

This paper introduces a universal labeling method for intracellular bacteria using a clickable methionine analog, overcoming limitations of fluorescence microscopy and antibody-based approaches.