Exploring the conformational landscape and stability of Aurora A using ion-mobility mass spectrometry and molecular modelling
L. J. Tomlinson, M. Bachelor, D. P. Byrne, J. Sarsby, P. J. Brownridge, R. Bayliss, P. A. Eyers, C. E. Eyers
This study uses ion-mobility mass spectrometry and molecular modeling to analyze conformational changes in Aurora A kinase induced by TPX2 activation and inhibitor binding.
Journal of the American Society for Mass Spectrometry · Jan 31, 2022Peer-reviewedBiochemistry