Author

S. N. Floor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Frost· 1 shared A. G. Myasnikov· 1 shared A. L. Gao· 1 shared A. Palla· 1 shared A. Sil· 1 shared A. Subramanian· 1 shared A. Xu· 1 shared C. A. Espinoza· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Frost

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

J. M. Liboy-Lugo, C. A. Espinoza, J. Sheu-Gruttadauria, J. E. Park, A. Xu, Z. Jowhar, A. L. Gao, J. A. Carmona-Negron, T. Wittmann, N. Jura, S. N. Floor

The paper identifies key residues in G3BPs that drive stress granule formation and gene expression changes under cellular stress, with G3BP2B showing specific roles in ER stress.

bioRxiv · Feb 6, 2024Cell Biology

A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response.

A. Subramanian, L. Wang, T. Moss, M. Voorhies, S. Sangwan, E. Stevenson, E. H. Pulido, S. Kwok, N. J. Krogan, D. L. Swaney, S. N. Floor, A. Sil, P. Walter, S. Mukherjee

This paper identifies SidI, a Legionella toxin that mimics tRNA, glycosylates the translation machinery, and triggers a ribotoxic stress response leading to cell death.

bioRxiv · Jun 10, 2022Cell Biology

Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance

K. Tsai, V. Stojkovic, L. Noda-Garcia, I. D. Young, A. G. Myasnikov, J. Kleinman, A. Palla, S. N. Floor, A. Frost, J. S. Fraser, D. S. Tawfik, D. Galonic Fujimori

This study uses directed evolution to identify Cfr variants that enhance rRNA methylation, revealing structural insights into antibiotic resistance mechanisms.

bioRxiv · Mar 12, 2021Biochemistry

Widespread translational remodeling during human neuronal differentiation

J. D. Blair, D. Hockemeyer, J. A. Doudna, H. S. Bateup, S. N. Floor

The paper investigates translational changes during human neuronal differentiation and identifies mTOR complex 1 signaling and 3' UTR regulation as key factors.

bioRxiv · Jun 26, 2017Cell Biology