Author

J. T. O'Connor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:Drosophila· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Page-McCaw· 3 shared M. S. Hutson· 3 shared A. C. Stevens· 2 shared A. D. Pumford· 1 shared E. K. Shannon· 1 shared F. B. Akbar· 1 shared I. Han· 1 shared J. Hua· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiophysics

A. Page-McCaw

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Author profile →

3 papers

Recent·Most cited

BiophysicsbioRxivMay 31, 2023

After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells

I. Han, J. Hua, J. S. White…·M. S. Hutson

This study shows that the GPCR Mthl10 and IP3 receptor are required for restoring cellular tension after wounding in Drosophila epithelial cells.

DOI 10.1091/mbc.e23-05-0204

Drosophilaimaging

𝕏 PostBluesky

BiophysicsbioRxivAug 24, 2022

A mathematical model of calcium signals around laser-induced epithelial wounds

A. C. Stevens, J. T. O'Connor, A. D. Pumford…·M. S. Hutson

The paper develops a mathematical model of calcium signals around laser-induced epithelial wounds in Drosophila, showing that cell-cell variability and IP3 transfer are necessary for coordinated signaling.

DOI 10.1091/mbc.e22-08-0361

Drosophilastatistical model

𝕏 PostBluesky

Cell BiologybioRxivDec 8, 2020

A protease-initiated model of wound detection

J. T. O'Connor, A. C. Stevens, E. K. Shannon…·A. Page-McCaw

The paper identifies a protease-initiated signal transduction pathway that enables epithelial cells to detect wounds through the activation of Gbp ligands and Mthl10 receptors, leading to calcium release.

DOI 10.1016/j.devcel.2021.06.020

proteomicsexperimental assay

𝕏 PostBluesky