Author

J. Hua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 2 Plant Biology· 2 Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:imaging· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

x. chen· 3 shared Y. Wang· 3 shared A. Lei· 2 shared A. Page-McCaw· 2 shared H. Li· 2 shared J. S. White· 2 shared J. Zhang· 2 shared K. J. Tro· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

x. chen

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Author profile →

10 papers

Recent·Most cited

GhCPK28 negatively regulates the immune response by phosphorylating GhTIFY3b

S. Gao, W. Shao, J. Wu, Z. Zhao, W. Hu, P. Shao, J. Hua, B. Zou, Q. Huang

This study identifies GhCPK28 as a negative regulator of cotton immunity against Verticillium dahliae by phosphorylating and destabilizing GhTIFY3b, enhancing resistance when silenced.

bioRxiv · Feb 23, 2024 · PreprintPlant Biology

Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

J. S. White, J. Hua, J. J. Su, K. J. Tro, E. M. Ruark, M. S. Hutson, A. Page-McCaw

The paper shows that wound-induced syncytia in Drosophila pupae close wounds faster than mononucleate cells by outpacing them and reducing intercalation needs.

bioRxiv · Jun 25, 2023Cell Biology

After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells

I. Han, J. Hua, J. S. White, J. T. O'Connor, L. S. Nassar, K. J. Tro, A. Page-McCaw, M. S. Hutson

This study shows that the GPCR Mthl10 and IP3 receptor are required for restoring cellular tension after wounding in Drosophila epithelial cells.

bioRxiv · May 31, 2023Biophysics

CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment

J. Li, T. Huang, J. Hua, Q. Wang, Y. Su, P. Chen, S. Bidlingmaier, A. Li, Z. Xie, A. Bidkar, S. Shen, W. Shi, Y. Seo, R. R. Flavell, D. Gioeli, , J. He

This paper develops and tests a CD46-targeted alpha radioimmunotherapy, 212Pb-TCMC-YS5, showing potent tumor growth inhibition and survival improvement in multiple prostate cancer models.

bioRxiv · Oct 14, 2022 · PreprintBioengineering

Deeply conserved super-enhancers maintain stem cell pluripotency in placental mammals

J. Zhang, J. Hua, W. Wang, M. Liao, N. Li, Y. Zhou, W. Yue, Z. Zhu, Q. Shen, S. Yu, X. Wu, Q. Pan, W. Xu, R. Zhang, X. Wu, , Y. Li

The paper identifies three deeply conserved super-enhancers in placental mammals that are essential for maintaining stem cell pluripotency.

bioRxiv · May 3, 2022 · PreprintCell Biology

Histone demethylase complexes KDM3A and KDM3B cooperate with OCT4/SOX2 to construct pluripotency gene regulatory network

Z. Zhu, X. Wu, Q. Li, J. Zhang, S. Yu, Q. Shen, Z. Zhou, Q. Pan, W. Yue, D. Qin, Y. Zhang, W. Zhao, R. Zhang, S. Peng, N. Li, , x. chen

The paper shows that KDM3A and KDM3B, along with OCT4/SOX2, regulate H3K9 methylation to maintain pluripotency in porcine-induced pluripotent stem cells.

bioRxiv · Aug 16, 2020Cell Biology

Comprehensive Live-cell Imaging Analysis of Cryptotanshinone and Synergistic Drug-Screening Effects in Various Human and Canine Cancer Cell Lines

H. Wilson-Robles, M. L. Bittner, R. Lopes, J. Hua, C. Sima, A. Datta

The paper evaluates the anticancer effects of Cryptotanshinone (CT) and synergistic drug combinations in human and canine cancer cell lines using live-cell imaging.

bioRxiv · Jun 30, 2020Cancer Biology

Tracing the origin of a new organ by inferring the genetic basis of rumen evolution

X. Pan, Y. Wang, Z. Li, X. Chen, R. Heller, N. Wang, C. Zhao, Y. Cai, H. Xu, S. Li, M. Li, C. Li, S. Hu, H. Li, K. Wang, , Y. Jiang

The paper investigates the genetic basis of rumen evolution by comparing transcriptomes and genomic data across ruminants, camels, and cetaceans, identifying key genetic innovations.

bioRxiv · Feb 19, 2020 · PreprintEvolutionary Biology

Development of a Surface Programmable Activation Receptor system (SPAR): A living cell biosensor for rapid pathogen detection

J. D. Kittle, J. S. Lwande, M. R. Williams, R. Brody, M. Frenchmeyer, J. Hua, S. Liang, K. McQuaide, M. Mo, A. Neese, Y. Tang, S. Vedamoorthy, L. Zeng, T. Zupancic, C. McBrairty

The paper develops a biosensor platform called SPAR for rapid and sensitive pathogen detection using engineered cells and antibodies.

bioRxiv · Jun 30, 2019 · PreprintBioengineering

QTL and genetic analysis controlling fiber quality traits using paternal backcross population in Upland cotton

J. Hua, L. Ma, Y. Su, Y. Wang, H. Nie, Y. Cui, C. Cheng, M. Wang

This study identifies novel and validated QTLs for fiber quality traits in Upland cotton using a paternal backcross population and RILs, with some QTLs explaining over 10% of phenotypic variation.

bioRxiv · Feb 18, 2019Plant Biology