M. S. Hutson

Piezo-dependent surveillance of matrix stiffness generates transient cells that repair the basement membrane

The paper shows that Piezo-dependent detection of matrix stiffness generates transient cells that repair basement membrane damage in Drosophila.

Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

The paper shows that wound-induced syncytia in Drosophila pupae close wounds faster than mononucleate cells by outpacing them and reducing intercalation needs.

After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells

This study shows that the GPCR Mthl10 and IP3 receptor are required for restoring cellular tension after wounding in Drosophila epithelial cells.

A mathematical model of calcium signals around laser-induced epithelial wounds

The paper develops a mathematical model of calcium signals around laser-induced epithelial wounds in Drosophila, showing that cell-cell variability and IP3 transfer are necessary for coordinated signaling.

Zones of Cellular Damage Around Pulsed-Laser Wounds

This study maps wound-induced cellular damage around laser wounds in Drosophila pupae, finding linear relationships between damage radii and wound size.

A protease-initiated model of wound detection

The paper identifies a protease-initiated signal transduction pathway that enables epithelial cells to detect wounds through the activation of Gbp ligands and Mthl10 receptors, leading to calcium release.

Elongated cells drive morphogenesis in a surface-wrapped finite element model of germband retraction

The paper uses a finite element model to show that elongated amnioserosa cells drive germband retraction in Drosophila, highlighting the importance of cell shape over force strength.