Cell BiologybioRxiv
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signalling
V. Chan, C. Camardi, K. Zhang…·R. J. Botelho
This study shows that LCLAT1 is required for EGF-mediated PtdIns(3,4,5)P3 generation and Akt signaling in cancer and retinal cells.
DOI 10.1091/mbc.e23-09-0361